
Stirred Tank Bioreactor
Description
Introduction of the Stirred tank bioreactor:
stainless steel the Stirred tank bioreactor are applied for fluid preparation for pharmaceutical, chemical, petroleum and food industries. With stainless steel as main material, the reactor is built with jacket for heating purpose and insulation layer for heat preservation, and is manufactured according to relative industrial standards such as GMP.
Features of the Stirred tank bioreactor:
1. Volume: 50-12000L
2. Material: SS316L & SS304
3. Insulation material: rock wool
4. Application: pharmaceutical, chemical, petroleum and food industries
5. Structure: Jacketed vessel, vessel with jacket and insulation
6. Finish: inside surface Ra 0.4~0.5μm by electro-polishing,outside surface Ra0.6~0.8μm by satin finish, or according to customer's requirements.
7. Components: mixing device, vent filter, temperature gauge, level gauge, manhole, sight glass with lamp and cleaning ball or according to client’s detailed requirements.
Vertical, ellipse top or flat top, support by legs or lifting lugs. Single wall, or with jacket, or with insulation. | |
Material | Material adopts S31603, or S30408. (Tai Steel or Bao Steel) |
Jacket Type | Full jacket, internal coil, external semi-coil, dimple jacket. |
Insulation | Adopts aluminum silicate or polyurethane, thickness 50 mm or 75 mm. |
Surface Finishing | Mechanical polishing, internal mirror polishing Ra 0.45; External matte, Ra 0.8 |
Heating Method | Steam heating, electric heating, thermal oil/hot water heating |
Agitation System | Adopt top center-entry agitator or side-entry agitator. |
Accessories | Condenser, Manhole, CIP spraying ball, thermometer, piezometer, air filter, sight glass, light, counter flange. |
Standard | All according to GMP requirements and GB150.1~4-2011 Design, Fabrication, Inspection and Acceptance. |
ODM | Can be customized according to customers requirement and product process. |
Main components and controls of system | |
1. On-line check and measure, and digitization fully automatic control; 2.PH, acid and base gang control. Peristaltic pump automatically adjust to feed acid and base; 3.Control range 2-12pH, measure precision±0.01 pH, control precision±0.02 pH; 4.It has auto alarm function. 5.pH sensor and signal transmission line, HAMILTON | |
DO | 1. On-line check and measure, cascade with rpm; digital display. 2.Range 0-100% or 0-200%, precision ±1%; 3.It has auto alarm function; 4.DO sensor and signal transmission line, HAMILTON |
Foam control | 1. Automatically control and automatically alarm; 2. Stainless steel electrode check, peristaltic pump automatically add defoamer. |
Feed control | 1. Automatically control and automatically alarm; 2.Stainless steel electrode check, peristaltic pump automatically feeding |
Temp. control | 1.PID fully digitization signal processing, digitization control settings 2.Circulating water automatically control temperature 3.Measure range 0-150°C, control range T+6-60°C,control precision±0.2°C 4.Pt 100Ωtemp. Sensor 5.system with electrical heater to control the temp inside vessel 6.water pump circulation, GRUNDFOS 7.solenoid valve to control |
Rotate speed | 1. Automatically control, with auto alarm function 2. Siemens frequency converter to adjust the speed. |
Pressure | 1 Manually adjusting with pressure gauge and manual valve (standard system) 2. Automatically adjusting with pressure transmitter and PID valve and pneumatic valves (optional) |
Air flow | 1.Manually adjusting with rotor meter and manual valve (standard system) 2.Automatically adjusting with mass-flow meter and pneumatic valves (optional) 3.Air in filter , tail gas filter , with SARTORIUS cartridge, precision 0.2μm |
Sterilization | 1.it can be SIP by connecting with steam 2.Manually control with manual valve (standard one) 3.Automatic control with pneumatic valves (optional) |
Control | Siemens PLC, and MCGSE 7"/10" LCD touch screen(HMI) and Daysly program |
PC | 1.PC with Kingview software for recording function (optional) 2.PC with Siemens remote control and Kingview recording function (optional) 3.printer (optional) |